MECOM Breakapart(3q) -

DESCRIPTION – the EVI1 (MECOM) break apart probe is a type of FISH (fluorescence in situ hybridization) test used to detect the rearrangement of EVI1 gene on chromosome number 3 at 3q26.6. it is a common disease in patient affected with AML (acute myeloid lymphoma) and MDS (myelodysplastic lymphoma)

METHODOLOGY – fluorescence in situ hybridization (FISH)

TURN AROUND TIME – 7 days

PATIENT PREPARATION –

COLLECT – non diluted bone marrow

SPECIMEN PREPARATION – 3-4 ml bone marrow or peripheral blood in green top (sodium heparin) or lavender top (EDTA) tube

STORAGE/TRANSPORT TEMPERATURE – 2-8 degrees C (with cold pack) and transport within 72 hours

STABILITY – ambient: 48 hours; refrigerated: 48 hours

UNACCEPTABLE CONDITIONS - clotted specimens

MRP – 4000.00

SPECIAL INSTRUCTIONS – clinical history is mandatory