FISH - 22q deletion orLSI Di George / VCFS

DESCRIPTION – this syndrome can cause heart defects, poor immune system function, a cleft palate and low levels of calcium in the blood. This syndrome is present in individual from birth.

CLINICAL UTILITY – deletions in 22q11.2 have been associated with several disorders including di-george and velocardiofcaial syndrome (VCF)

METHODOLOGY – fluorescence in situ hybridization (FISH)

TURN AROUND TIME – 9 days

PATEINT PREPARATION –

COLLECT – non diluted bone marrow aspirate

SPECIMEN PREPARATION – 3-5 ml peripheral blood in green top (sodium heparin)

STORAGE/TRANSPORT TEMPERATURE – ambient 8-25 degrees C

STABILITY – ambient: 48 hours; refrigerated: 48 hours

UNACCEPTABLE CONDITIONS – clotted specimens

MRP – 5799.00

SPECIAL INSTRUCTIONS – dully filled chromosome and FISH analysis test request form is mandatory