CD1a (histiocytosis)

CD1A (HISTIOCYTOSIS)

Description

Nonpolymorphic

MHC class I-related cell-surface glycoprotein

Expressed by interdigitating reticulum cells, cortical

thymocytes

,

thymomas

, Langerhans cells, and Langerhans

histiocytosis

cells (

histiocytosis

X)

Aids in identifying some T-cell lymphomas and

leukemias

Methodology: Immunohistochemistry

TAT: 3-5 days

Specimen Preparation
Collect - tissue /or cell
Specimen Preparation- formal fix (10 % neutral buffered formalin) and paraffin enter specimen (FFPE specimens square measure needed). shield paraffin block or slides from uncontrolled heat. Transport tissue block or five unstained (3-micron thick sections), charged slides during a tissue transport kit. (Min: a pair of slides). If causing precut slides, don't over heat it.
Storage/Transport Temperature- At temperature or cold. Transport it in cooled instrumentation throughout weather.
Unacceptable conditions- i) Specimens submitted with non-marked/tagged tissue sort square measure rejected.
ii) Depleted specimens aren't tested.
Stability- i) Ambient: Indefinitely;
ii) Refrigerated: Indefinitely;
iii) Frozen: Unacceptable