13q deletion

DESCRIPTION – 13 q deletion is detected in 15-20% of multiple myeloma patients by conventional karyotype and in 33-52% cases by FISH analysis.

CLINICAL UTILITY – 13q deletion is used for the diagnosis and prognosis of prostate cancer

METHODOLOGY – fluorescence in situ hybridization (FISH)

TURN AROUND TIME – 7 days

PATIENT PREPARATION –

COLLECT – non diluted bone marrow aspirate

SPECIMEN PREPARATION – transfer 3 ml bone marrow or 5 ml whole blood

STORAGE/TRANSPORT TEMPERATURE – room temperature (18-25 degrees C)

STABILITY – ambient: 48 hours; 48 hours

UNACCEPTABLE CONDITIONS – clotted specimens

MRP – 1800.00

SPECIAL INSTRUCTIONS – clinical history is mandatory including surgical pathology reports